Our lab mainly studies the pathogenesis of important infectious diseases caused by bacteria. In particular, we are interested in bacterial exotoxins, which promote the happening and development of infectious diseases by directly damaging host cells, impairing immune systems, or even leading to diseases alone. We focus on investigating the molecular, structural, and cellular mechanisms of how bacterial toxins and effector proteins target and affect important cellular functions. Along the lines of basic research, we are also keen on translating our insights and knowledge toward developing new scientific tools as well as novel therapeutics.

The  current research areas of his lab include:

(1) Basic study on the molecular  mechanism of bacterial toxin actions； 

(2) Translational research on developing novel applications based on toxins；

(3) Basic principles of host-microbiota interactions.